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Highlights

  • Purpose-built adaptive reuse project blending lab, R&D, and creative office environments.
  • High-speed fiber internet and substantial back-up generator support uninterrupted efficiency.
  • Accessible to Union Station, major Metrolink lines, and regional freeway systems.
  • Customizable spaces with BSL-1 and BSL-2 capabilities for advanced life science operations.
  • Situated within the Los Angeles Bioscience HUB, enabling proximity to academic institutions.
  • On-site surface parking and commuter connectivity facilitate seamless transportation access.

Features

Clear Height
20’
Drive In Bays
5
Exterior Dock Doors
1

All Available Spaces(4)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 1st Floor - A2
  • 1,724 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Full Build-Out
  • Now
  • Can be combined with additional space(s) for up to 9,159 SF of adjacent space
  • 1st Floor - B
  • 3,633 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Full Build-Out
  • Now
  • Can be combined with additional space(s) for up to 9,159 SF of adjacent space
  • 1st Floor - C2
  • 1,583 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Full Build-Out
  • Now
  • Can be combined with additional space(s) for up to 9,159 SF of adjacent space
  • 1st Floor - G
  • 2,219 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Full Build-Out
  • Now
  • Can be combined with additional space(s) for up to 9,159 SF of adjacent space
Space Size Term Rental Rate Space Use Build-Out Available
1st Floor - A2 1,724 SF Negotiable Upon Request Upon Request Upon Request Upon Request Flex Full Build-Out Now
1st Floor - B 3,633 SF Negotiable Upon Request Upon Request Upon Request Upon Request Flex Full Build-Out Now
1st Floor - C2 1,583 SF Negotiable Upon Request Upon Request Upon Request Upon Request Flex Full Build-Out Now
1st Floor - G 2,219 SF Negotiable Upon Request Upon Request Upon Request Upon Request Flex Full Build-Out Now

1st Floor - A2

Size
1,724 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Build-Out
Full Build-Out
Available
Now

1st Floor - B

Size
3,633 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Build-Out
Full Build-Out
Available
Now

1st Floor - C2

Size
1,583 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Build-Out
Full Build-Out
Available
Now

1st Floor - G

Size
2,219 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Build-Out
Full Build-Out
Available
Now

1st Floor - A2

Size 1,724 SF
Term Negotiable
Rental Rate Upon Request
Space Use Flex
Build-Out Full Build-Out
Available Now

  • Can be combined with additional space(s) for up to 9,159 SF of adjacent space

1st Floor - B

Size 3,633 SF
Term Negotiable
Rental Rate Upon Request
Space Use Flex
Build-Out Full Build-Out
Available Now

  • Can be combined with additional space(s) for up to 9,159 SF of adjacent space

1st Floor - C2

Size 1,583 SF
Term Negotiable
Rental Rate Upon Request
Space Use Flex
Build-Out Full Build-Out
Available Now

  • Can be combined with additional space(s) for up to 9,159 SF of adjacent space

1st Floor - G

Size 2,219 SF
Term Negotiable
Rental Rate Upon Request
Space Use Flex
Build-Out Full Build-Out
Available Now

  • Can be combined with additional space(s) for up to 9,159 SF of adjacent space

Property Overview

This property at 5370 Alhambra Avenue represents an adaptive reuse opportunity designed for the thriving life sciences and innovation sector in Los Angeles. Situated in the El Sereno neighborhood within the LA Bioscience HUB, the asset provides a flexible environment tailored to companies transitioning from incubator programs into larger, scalable facilities. Originally built in 1937 and thoughtfully redeveloped by HATCHspaces®, the site delivers a blend of lab and creative office areas in a multi-tenant configuration. With customizable lockout suites, BSL-1 and BSL-2 capabilities, and high-speed fiber connectivity, the building supports advanced research and tech development operations. A robust back-up generator ensures power continuity for sensitive processes, while curated layouts accommodate growth trajectories for life science firms. The location offers convenient access to regional transportation, including Union Station just under five miles away, as well as proximity to key Metro lines and major highways serving Downtown Los Angeles and surrounding markets. Tenants benefit from connectivity to academic hubs and resources, making this property an agile solution for expanding bioscience and technology enterprises.

Property Facts

Building Size
19,056 SF
Lot Size
0.50 AC
Year Built/Renovated
1937/2000
Construction
Wood Frame
Zoning
MR1, Los Angeles - MR1, Los Angeles

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 1st
  • Los Angeles Bioscience Hub
  • Services
  • 2nd
  • TCR Cure Bio Pharma
  • Professional, Scientific, and Technical Services
Fairly walkable
40/100
Exceptionally drivable
90/100
Some public transit
40/100
Fairly bikeable
40/100
  • Listing ID: 40712046

  • Date on Market: 5/29/2026

  • Last Updated:

  • Address: 5370 Alhambra Ave, Los Angeles, CA 90032

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